Bringing accuracy to PET reconstruction
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Effect of Post-Reconstruction Gaussian Filtering on Image Quality and Myocardial Blood Flow Measurement with N-13 Ammonia PET
Objective(s): In order to evaluate the effect of post-reconstruction Gaussian filtering on image quality and myocardial blood flow (MBF) measurement by dynamic N-13 ammonia positron emission tomography (PET), we compared various reconstruction and filtering methods with image characteristics. Methods: Dynamic PET images of three patients with coronary artery disease (male-female ratio of 2:1; a...
متن کاملMR-guided joint reconstruction of activity and attenuation in brain PET-MR
With the advent of time-of-flight (TOF) PET scanners, joint maximum-likelihood reconstruction of activity and attenuation (MLAA) maps has recently regained attention for the estimation of PET attenuation maps from emission data. However, the estimated attenuation and activity maps are scaled by unknown scaling factors. We recently demonstrated that in hybrid PET-MR, the scaling issue of this al...
متن کاملThe influence of using different reconstruction algorithms on sensitivity of quantitative 18F-FDG-PET volumetric measures to background activity variation
Introduction: This study aims to investigate the influence of background activity variation on image quantification in differently reconstructed PET/CT images. Methods: Measurements were performed on a Discovery-690 PET/CT scanner using a custom-built NEMA-like phantom. A background activity level of 5.3 and 2.6 kBq/ml 18F-FDG were applied. Ima...
متن کاملImpact of Various Image Reconstruction Methods on Joint Compensation of Respiratory Motion and Partial Volume Effects in Whole-Body 18F-FDG PET/CT Imaging: Patients with Non-Small Cell Lung Cancer
Background: The present study aims to assess the impact of various image reconstruction methods in 18F-FDG PET/CT imaging on the quantification performance of the proposed technique for joint compensation of respiratory motion and partial volume effects (PVEs) in patients with non-small cell lung cancer. Materials and Methods: An image-based deconvolution technique was proposed, incorporating w...
متن کاملEdge Artifacts in Point Spread Function-based PET Reconstruction in Relation to Object Size and Reconstruction Parameters
Objective(s): We evaluated edge artifacts in relation to phantom diameter and reconstruction parameters in point spread function (PSF)-based positron emission tomography (PET) image reconstruction.Methods: PET data were acquired from an original cone-shaped phantom filled with 18F solution (21.9 kBq/mL) for 10 min using a Biograph mCT scanner. The images were reconstructed using the baseline or...
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