3D Microelectrode Geometry Effects the Multilayer Dense Osteo Intra-organelle Membrane Potential Characterization
نویسندگان
چکیده
We report the computational simulation study for the characterization of multilayer dense osteoblast intra organelle membrane potential in different microelectrode. The response of a cell model at various frequencies and the effect of cell parameters, such as cell membrane resistance and capacitance, were studied. We show that at low frequencies—the intra organelle can be electro porated while at high frequencies, the induced potential can be much lower than that at low frequencies at same applied voltage for dense osteo cells . we also find out that the induced TMP of osteoblast cell depends not only on its radius and geometry of the microelectrode but also the resistances and capacitances of suspending medium, which effects the dielectric property of osteoblast cell.
منابع مشابه
Study of Intra organelle Nanoporation of Multilayer Dense Osteoblast Cell
This research paper represents the theoretical and experimental study of intra organelle nano poration of multi layer osteoblast cell .It is observed that the Pico pulse has the remarkable response for nano pores generation on the intra organelle and chemicals are entered into the cell. The reported study encourage that the efficiency of nanoporation can be control by the specification of micro...
متن کاملFabrication and Characterization of Chitosan/Alginate Multilayer Composite Membrane Supported by a Porous Poly (Acrylonitrile) Substrate for Pervaporation Dehydration of Alcohol
Chitosan (CS) and alginate (Alg) are complementary in their membrane performance, but the combination of them is normally difcult to use due to their different solubilities. Layer-by-Layer deposition appears to be an effective method for improving the separation efciency of a composite membrane. In this work, the polyelectrolyte multilayer composite membranes (PEMCMs) wer...
متن کاملCrocin Prevents Sub-Cellular Organelle Damage, Proteolysis and Apoptosis in Rat Hepatocytes: A Justification for Its Hepatoprotection
Crocin, the main constituent of saffron (Crocus sativus L.), is a natural carotenoid which is known for its antioxidant activity. Liver as the organ that metabolizes many chemicals is one of the first position that is at risk of environmental pollutants. It is clear that compounds that exhibit antioxidant properties, scavenging of free radicals and inhibition of lipid peroxidation are expected ...
متن کاملCrocin Prevents Sub-Cellular Organelle Damage, Proteolysis and Apoptosis in Rat Hepatocytes: A Justification for Its Hepatoprotection
Crocin, the main constituent of saffron (Crocus sativus L.), is a natural carotenoid which is known for its antioxidant activity. Liver as the organ that metabolizes many chemicals is one of the first position that is at risk of environmental pollutants. It is clear that compounds that exhibit antioxidant properties, scavenging of free radicals and inhibition of lipid peroxidation are expected ...
متن کاملSynthesis of a Multilayer Ceramic Membrane Used for Hydrogen Separation at High Temperature
A multilayer composite ceramic membrane was prepared by depositing a nano-scale layer of SiO2 on top of a modified porous alumina support by chemical vapor deposition (CVD) method. The modification of the support was carried out by adding a graded layer of Al2O3 (γ-alumina phase), using sol-gel method. An optimized temperature of 700 K for intermediate layer calcination was gained by XRD analys...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2013