Oral Submucous Fibrosis: an Update on Etiology and Pathogenesis-a Review
نویسنده
چکیده
24 Review Article ORAL SUBMUCOUS FIBROSIS: AN UPDATE ON ETIOLOGY AND PATHOGENESIS-A REVIEW Shukla A, Singh A, Srivastava R Abstract: Oral submucous fibrosis (OSMF) is a chronic disease of oral mucosa characterized by inflammation and progressive fibrosis followed by stiffening of an otherwise yielding mucosa resulting in difficulty in opening the mouth. It is generally accepted today that areca nut quid plays a major role in the etiology. The pathogenesis of the disease is not well established, but the cause of OSMF is believed to be multifactorial. Ingestion of chillies, genetic susceptibility, nutritional deficiencies, and autoimmunity and collagen disorders may be involved in the pathogenesis of this condition. The purpose of this review is to analyze critically the recent developments that may lead to understanding of etiology of OSMF. The review article has been prepared doing a literature review from the World Wide Web and pubmed/medline.
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A Review of Oral Submucousal Fibrosis, Related Factors, Prognosis and New Therapeutic Approaches
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