Synthesis and pharmacological analysis of high affinity melatonin receptor ligands.
نویسندگان
چکیده
We report the synthesis and radioligand binding analysis of a series of naphthalenic melatonin receptor ligands, N-[2-(7-alkoxy-2-methoxy-1-naphthyl)ethyl]propionamide. This series of ligands exhibits subpicomolar binding affinity to both MT1 and MT2 melatonin receptors expressed in chinese hamster ovary (CHO) cells.
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 50 2 شماره
صفحات -
تاریخ انتشار 2002