Therapeutic applications of ricin and some alkaloids
نویسندگان
چکیده
Ricin is one of the most known toxic materials of plant origin. The 2007 Guinness World Records Book considers ricin the world's most potent plant toxin. It also possesses wide-ranging biological effects on higher organisms and it is a powerful inhibitor of cellular protein synthesis. Ricin is frequently therapeutically used in the construction of immunotoxins designed to kill specific target cells such as cancer cells. Some alkaloids such as nicotine, atropine and ergots have also shown various toxicities and side effects associated with their use. Instead of the various toxicities and side effects, these alkaloids have wide therapeutic potentials for various diseases. These have shown very good therapeutic potentials for the treating nicotine dependence, acetylcholinestrase poisoning, cardiac, respiratory and urinary affections, hyperhydrosis, pain, termination of labour, migraine, postural hypertension etc.
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