Coexpression and Relative Abundance Defined by B Cell Transcription Factor Stages of Germinal Center Transit Are
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چکیده
منابع مشابه
Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance.
The transit of T cell-activated B cells through the germinal center (GC) is controlled by sequential activation and repression of key transcription factors, executing the pre- and post-GC B cell program. B cell lymphoma (BCL) 6 and IFN regulatory factor (IRF) 8 are necessary for GC formation and for its molecular activity in Pax5+PU.1+ B cells. IRF4, which is highly expressed in BCL6- GC B cell...
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