Treatment of idiopathic inflammatory myopathies.

Approach to Diagnosis and Management of an Idiopathic Inflammatory Myopathy

Idiopathic inflammatory myopathies are a group of autoimmune diseases characterized by proximal muscle weakness and inflammation of skeletal muscle. Specific forms of idiopathic inflammatory myopathy include polymyositis, dermatomyositis, and inclusion body myositis. Inflammatory myopathies have a bimodal distribution, occurring in patients between 10 and 15 years and 45 and 60 years of age, ex...

The idiopathic inflammatory myopathies and their treatment.

Current pharmacological treatment of idiopathic inflammatory myopathies.

The idiopathic inflammatory myopathies are uncommon and heterogeneous disorders. Their classification is based on distinct clinicopathologic features. Although idiopathic inflammatory myopathies share some similarities, different subtypes may have variable responses to therapy, so it is very important to distinguish the correct subtype. There are few randomised, double blind placebo controlled ...

One year in review 2017: idiopathic inflammatory myopathies.

Every year new concepts about pathogenesis, serology, diagnosis and treatment in inflammatory myopathies (IIMs) have been provided. The purpose of this manuscript is to summarise the most relevant literature contributions published over the last year about these complex and rare diseases.

Deciphering the clinical presentations, pathogenesis, and treatment of the idiopathic inflammatory myopathies.

The idiopathic inflammatory myopathies or myositis syndromes (the most common forms are polymyositis, dermatomyositis, and inclusion body myositis) are systemic autoimmune diseases defined by chronic muscle weakness and inflammation of unknown etiology and result in significant morbidity and mortality. Research suggests that categorizing heterogeneous myositis syndromes into mutually exclusive ...

Idiopathic infl ammatory myopathies : An update

Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of disease with complex clinical features. The histological features of them usually include various degrees of degenerative changes and inflammatory (usually lymphocytic) infiltrates [1]. Histopathological evaluation is one of the key tools for the diagnosis of IIM. Because of the complexity of clinical, morphological and labor...