Primary Diffuse Leptomeningeal Gliomatosis: Report of a Case Presenting with Chronic Meningitis
نویسندگان
چکیده
Neoplastic meningitis occurs in approximately 5% of patients with cancer. Primary diffuse leptomeningeal gliomatosis is a rare condition whereby a glioma arises from heterotopic cell nests in the leptomeninges. We report here a case presenting with clinical features similar to those of chronic infectious meningitis without positive cerebrospinal fluid cytology. Neurological signs in our patient deteriorated progressively without responding to antitubercular, antiviral, or antibiotic therapy. Leptomeningeal biopsy sampling revealed the condition to be primary diffuse leptomeningeal gliomatosis.
منابع مشابه
Disseminated primary diffuse leptomeningeal gliomatosis: a case report with liquid based and conventional smear cytology
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Dr. André Leite Gonçalves – Division of Child Neurology / Departamento de Neurologia e Neurocirurgia Rua Botucatu 720 – 04023-900 São Paulo SP Brasil. E-mail: [email protected] Glioma arising primarily from the leptomeninges is extremely rare and often diagnosed only in postmortem examination. It is thought to derive from heterotopic nests of neuroglial tissue within the leptomeninges, w...
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