Self-assembly of DNA double-double crossover complexes into high-density, doubly connected, planar structures.
نویسندگان
چکیده
We designed a molecular complex, the double-double crossover, consisting of four DNA double helices connected by six reciprocal exchanges. Atomic force micrographs suggest that double-double crossover complexes self-assemble into high-density, doubly connected, two-dimensional, planar structures. Such structures may be suitable as substrates for the deposition of nanomaterials in the creation of high-density electrical and quantum devices. We speculate about a modified double-double crossover complex that might self-assemble into high-density, doubly connected, three-dimensional structures.
منابع مشابه
DNA triangles and self-assembled hexagonal tilings.
We have designed and constructed DNA complexes in the form of triangles. We have created hexagonal planar tilings from these triangles via self-assembly. Unlike previously reported structures self-assembled from DNA, our structures appear to involve bending of double helices. Bending helices may be a useful design option in the creation of self-assembled DNA structures. It has been suggested th...
متن کاملBuilding Blocks for DNA Self-Assembly
DNA complexes, like the double crossover, are used as building blocks for the assembly of higher-order structures. Currently, the number of experimentally proven reliable complexes is small. We have begun work on expanding the collection of such complexes. Here we report on our design concepts and initial experiments. In particular, we present experimental evidence of two new complexes: quadrup...
متن کاملSelf-assembly of fully addressable DNA nanostructures from double crossover tiles
DNA origami and single-stranded tile (SST) are two proven approaches to self-assemble finite-size complex DNA nanostructures. The construction elements appeared in structures from these two methods can also be found in multi-stranded DNA tiles such as double crossover tiles. Here we report the design and observation of four types of finite-size lattices with four different double crossover tile...
متن کاملIntegrating DNA strand-displacement circuitry with DNA tile self-assembly
DNA nanotechnology has emerged as a reliable and programmable way of controlling matter at the nanoscale through the specificity of Watson-Crick base pairing, allowing both complex self-assembled structures with nanometer precision and complex reaction networks implementing digital and analog behaviors. Here we show how two well-developed frameworks, DNA tile self-assembly and DNA strand-displa...
متن کاملRelics of the Antarctic tundra
Many viruses have capsids that are icosahedra: 20-sided nearspheres with triangular faces. Chuan Zhang et al. have created icosahedra consisting purely of DNA, which self-assemble from five-pointed molecular tiles. The authors’ previous research with three-pointed tiles showed that triangular faces make extremely stable building blocks. In the present work, they designed fivepointed tiles using...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of the American Chemical Society
دوره 127 50 شماره
صفحات -
تاریخ انتشار 2005