Experimental Studies on Artemisia Vulgaris – a Possible Antifertility Drug
نویسندگان
چکیده
The effect of alcoholic extract of the aerial parts of Artemisia vulgaris Linn on estrous cycle and implantation, in female albino rats, was studied. The drug induced an irregular estrous cycle with random disappearance of estrous phase and increase in the number of metestrus phases within the estrous cycle, observed for the total test period of 18 days. It exhibited 80% anti-implantation activity without showing any gross malformations in pups delivered, possibly due to its non-toxic nature even at the high dose of 3000 mg/kg p.o. These facts suggest the drug to possess some antifertility effect.
منابع مشابه
Antimalarial properties of Artemisia vulgaris L. ethanolic leaf extract in a Plasmodium berghei murine malaria model.
BACKGROUND & OBJECTIVES Artemisinin isolated from Artemisia annua is the most potent antimalarial drug against chloroquine-resistant Plasmodium falciparum malaria. Artemisia vulgaris, an invasive weed, is the only Artemisia species available in Sri Lanka. A pilot study was undertaken to investigate the antiparasitic activity of an A. vulgaris ethanolic leaf extract (AVELE) in a P. berghei ANKA ...
متن کاملInhibitory effect of n-hexane: ethyl acetate fraction from Artemisia vulgaris L. on cell culture of oral epithelial carcinoma
Background: Sudamala herb (Artemisia vulgaris L.) is often used in society as an anti tumor for organs of digestive system including oral cavity. Nevertheless, there are still no further scientific researches on active materials which can be used as anti carcinogen in oral cavity. Most of anti carcinogens are actually obtained from the genus Artemisia. Moreover, in Indonesia, the species of the...
متن کاملPlant products impairing fertility of animals.
Fertility is possibly the most important capability contained within living cells or species. Therefore, finding the most efficacious way to enhance or promote fertility is the main goal of all living things. To best manage nature's strong predisposition for fertility, plant-based traditional medicines for birth control have long been incorporated into medical practices throughout the world, in...
متن کاملArtemisia vulgaris L. ethanolic leaf extract reverses thrombocytopenia/thrombocytosis and averts end-stage disease of experimental severe Plasmodium berghei murine malaria.
BACKGROUND & OBJECTIVES Artemisinin isolated from Artemisia annua is the most potent antimalarial against chloroquine resistant Plasmodium falciparum malaria. We previously reported that the ethanolic leaf extract of Artemisia vulgaris, an invasive weed and the only Artemisia species in Sri Lanka, possess both potent and safe antimalarial activity (in terms of antiparasitic properties) in a P. ...
متن کاملFlowering phenology and potential pollen emission of three Artemisia species in relation to airborne pollen data in Poznań (Western Poland)
Artemisia pollen is an important allergen in Europe. In Poznań (Western Poland), three Artemisia species, A. vulgaris, A. campestris and A. absinthium, are widely distributed. However, the contributions of these species to the total airborne pollen are unknown. The aim of the study was to determine the flowering phenology and pollen production of the three abovementioned species and to construc...
متن کامل