Effect of peritumoral tissue infiltration with radioactive yttrium on growth and spread of malignant cells.

peritoneally or intrapleurally into mice or patients bearing cancerous effusions remains largely local ized in the cavity and therefore can be used suc cessfully for intracavitary tumor therapy. Later (3, 9, 10), similar intracavitary retention of radio active material, suggesting analogous therapeutic application, was obtained with particle suspen sions of radioactive chromic phosphate (CrP3204). Recently, the pioneer experiments (14-16) on the therapeutic use of radioactive yttrium chloride (Y90C13)revealed a copious retention in situ when