The Mare Reproductive Loss Syndrome (MRLS) and the Eastern Tent Caterpillar: Immunological Testing of Aborting Mares
نویسندگان
چکیده
Mare reproductive loss syndrome (MRLS) describes a condition of equine early-term and late-term fetal losses in which the etiology has not been fully characterized. Involvement of Eastern tent caterpillars (ETC) has been highly considered because oral administration of ETC rapidly induces abortion in pregnant mares. Pathologic lesions observed in placental and fetal tissues of horses with characteristics of MRLS were consistent with bacterial infection. In addition, a small percentage of the naturally affected MRLS horses developed metritis, pericarditis, and/or unilateral uveitis.
منابع مشابه
Invited review: the role of caterpillars in mare reproductive loss syndrome: a model for environmental causes of abortion.
A new abortigenic disease, now known as mare reproductive loss syndrome (MRLS), significantly affected the horse industry in the Ohio River Valley of the United States in late April and early May of 2001 and 2002. In 2001, approximately 25% of all pregnant mares aborted within several weeks (over 3,000 mares lost pregnancies), and abortion rates exceeded 60% on some farms. Mare reproductive los...
متن کاملThe Mare Reproductive Loss Syndrome and the Eastern Tent Caterpillar II: A Toxicokinetic/Clinical Evaluation and a Proposed Pathogenesis: Septic Penetrating Setae
Reviewing the mare reproductive loss syndrome (MRLS), it is proposed that the fundamental mechanism of this syndrome, which includes early fetal loss, late fetal loss, uveitis, pericarditis, and encephalitis, is tissue penetration by septic barbed setal fragments (septic penetrating setae) from Eastern tent caterpillars (Malacosoma americanum). Once ingested, these barbed setal fragments migrat...
متن کاملThe mare reproductive loss syndrome and the eastern tent caterpillar: a toxicokinetic/statistical analysis with clinical, epidemiologic, and mechanistic implications.
During 2001, central Kentucky experienced acute transient epidemics of early and late fetal losses, pericarditis, and unilateral endophthalmitis, collectively referred to as mare reproductive loss syndrome (MRLS). A toxicokinetic/statistical analysis of experimental and field MRLS data was conducted using accelerated failure time (AFT) analysis of abortions following administration of Eastern t...
متن کاملCase-control study of factors associated with excessive proportions of early fetal losses associated with mare reproductive loss syndrome in central Kentucky during 2001.
OBJECTIVE To identify factors associated with excessive proportions of early fetal losses associated with mare reproductive loss syndrome in central Kentucky during 2001. DESIGN Case-control study. PROCEDURE Questionnaires were used to collect information on farm-, pasture-, and individual animal-level factors purportedly associated with mare reproductive loss syndrome. Data were collected ...
متن کاملSperm Transport in the Mare Reproductive Tract: A Review
The objective of this study was to review the literature on sperm transport in the mare. During this process the sperm cells must reach the oviducts in order to fertilize the oocyte, but before reaching this site it must go through the uterus that is a hostile environment at this moment since there is an inflammatory reaction in this location that aims to eliminate excess spermatozoa and bacter...
متن کامل