Concurrent Medullary, Papillary, and Follicular Thyroid Carcinomas and Simultaneous Cushing’s Syndrome

Background: Papillary thyroid carcinoma is the most common thyroid cancer (85%). Follicular thyroid carcinoma is the second most common type of thyroid cancer, accounting for up to 10% of all thyroid cancers. Medullary thyroid carcinoma accounts for only 5–8% of thyroid cancers. Concurrent medullary, follicular, and papillary carcinomas of the thyroid Received: April 22, 2014 Accepted after revision: September 29, 2014 Published online: November 22, 2014 Haggi Mazeh, MD Department of Surgery Hadassah University Hospital Mount Scopus PO Box 24035, Jerusalem 91240 (Israel) E-Mail hmazeh @ hadassah.org.il © 2014 European Thyroid Association Published by S. Karger AG, Basel 2235–0640/14/0041–0065$39.50/0 www.karger.com/etj What Is Known about This Topic? • Only two cases of concurrent papillary, follicular, and medullary thyroid cancer have been described. What Does This Case Report Add? • This is the first reported case of a patient with follicular, papillary, and medullary thyroid carcinoma, and Cushing’s syndrome. Although no associated genetic mutation is currently known, this may very well be the first report of a new syndrome. D ow nl oa de d by : 54 .7 0. 40 .1 1 10 /6 /2 01 7 5: 36 :3 3 P M