Use of Mitochondrial DNA in Forensic Odontology: A Review
نویسنده
چکیده
The advent of DNA typing has revolutionized law enforcement. The identification of dead bodies in mass casualties has been a Herculean task since time immemorial. Fatal crash of civil or military airliners generally leaves numerous unidentified bodies. Despite the fact that the inner of the teeth is relatively protected against external influence, the DNA of the pulpal tissue can be harmed so much that the DNA analysis are made impossible. Studies have shown that the dentine is a good source of mitochondrial DNA (mt DNA) and mitochondrial DNA presents several advantages compared to nuclear DNA (nu DNA),when teeth are used for identification purposes There are indications of presence of heteroplasmy in mitochondrial DNA. This may have an impact on the interpretation of the analysis of results.
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