PCR and restriction endonuclease assay for detection of a novel mutation associated with sulfonamide resistance in Neisseria meningitidis.
نویسندگان
چکیده
We identified a previously undocumented mutation in the dihydropteroate synthase (folP) gene associated with Neisseria meningitidis sulfonamide resistance. A PCR-based assay to detect this mutation, which is 100% predictive of sulfonamide resistance, was developed.
منابع مشابه
Plasmid-mediated sulfonamide resistance in Neisseria meningitidis.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 47 10 شماره
صفحات -
تاریخ انتشار 2003