Patent Foramen Ovale
نویسندگان
چکیده
The patent foramen ovale (PFO) is a normal interatrial communication during fetal life that persists after birth in approximately 1 of every 4 adults. PFO is a potential route for embolic transit from the systemic venous circulation to the brain. Though there is compelling circumstantial evidence implicating PFO, the precise role of PFO in the pathogenesis of cryptogenic stroke is not yet established. Several randomized trials of transcatheter PFO closure versus medical management are ongoing. Results of these trials may improve our ability to select the best treatment for individual patients. Further well-designed studies are necessary to address several unresolved issues related to PFO stroke and PFO migraine pathophysiology, and to identify the patients who would most likely benefit from PFO closure. The purpose of this review is to summarize contemporary understanding, discuss current treatments, and explore some of the knowledge gaps pertaining to the clinical significance of PFO. (J Am Coll Cardiol 2012;59:1665–71) © 2012 by the American College of Cardiology Foundation Published by Elsevier Inc. doi:10.1016/j.jacc.2011.09.085
منابع مشابه
Heart Carcinoid Disease with Patent Foramen Ovale Treated by Mini Sternotomy
This case report was an attempt to present the importance of diagnostic echocardiography and closure of a patent foramen ovale in carcinoid heart disease. Herein, we present a case of a 48-year-old woman with a carcinoid metastasis presenting with tricuspid regurgitation, pulmonic stenosis, patent foramen ovale, and borderline left ventricular ejection fraction on an echocardiogram. Surgical in...
متن کاملPatent foram An endovascular device to close a patent foramen ovale : b
An endovascular device to close a patent foramen ovale: b
متن کاملPatent Foramen Ovale and Brain Infarct
Background and Purpose Paradoxical embolism through a patent foramen ovale is a recognized cause of stroke, but clinical predictors, recurrence rate, and prevention of brain infarcts in patients with patent foramen ovale have not been determined. We reviewed transesophageal echocardiographic records to ascertain echocardiographic predictors and optimal prophylaxis for patent foramen ovale-relat...
متن کاملRelation between directly detected patent foramen ovale and ischemic brain lesions in sport divers.
BACKGROUND In divers, the significance of a patent foramen ovale and its potential relation to paradoxical gas emboli remain uncertain. OBJECTIVE To assess the prevalence of symptoms of decompression illness and ischemic brain lesions in divers with regard to the presence of a patent foramen ovale. DESIGN Retrospective cohort study. SETTING University hospital and three diving clubs in Sw...
متن کاملفراوانی آنومالی های سپتوم بین دهلیزی در بیماران با حوادث آمبولیک مغزی با علت ناشناخته با اکوکاردیوگرافی ترانس توراسیک و ترانس ازوفاژیال، بیمارستان امام تهران
Atrial septal anomalies suggested to play important role in enhancing tendency to induce cerebral embolic events. This study was undertaken to find the frequency of atrial septal anomalies including Patent Foramen Ovale, Atrial Septal Aneurysm and Atrial Septal Defect in patients with etiologically unknown stroke categorized as cryptogenic.Materials and Methods: 32 patients were studied by tran...
متن کامل