Microwave-assisted amination of a chloropurine derivative in the synthesis of acyclic nucleoside analogues.
نویسندگان
چکیده
An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compounds.
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ورودعنوان ژورنال:
- Molecules
دوره 10 2 شماره
صفحات -
تاریخ انتشار 2005