Hedgehog Signaling: Costal-2 Bridges the Transduction Gap
نویسنده
چکیده
Drosophila genetics has provided the Hedgehog signaling pathway with roughly ordered components, but few mechanistic connections. Several studies now show that the kinesin-related protein Costal-2 provides a physical link between the transmembrane transducer Smoothened and the transcriptional effector Cubitus interruptus.
منابع مشابه
Regulation of mammalian Gli proteins by Costal 2 and PKA in Drosophila reveals Hedgehog pathway conservation.
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ورودعنوان ژورنال:
- Current Biology
دوره 14 شماره
صفحات -
تاریخ انتشار 2004