Evaluation of Salivary Anti-Ccp in Rheumatoid Arthritis Patients

Aim and objective: The aimof this study was to evaluate the levels of salivary anti-cyclic citrullinated peptide (anti-CCP) in Rheumatoid Arthritis patients. The salivary anti-CCP level was compared with the serum values. Materials and method: saliva and serum samples were collected from 30 rheumatoid arthritis (group R) patients and 30 controls (group C). The samples were analysed by chemiluminescent micro particle immunoassay method. The results were compared and statistically analyzed. Results: On comparing saliva and serum in controls, p-value was 0.195, was statiscally insignificant. Serum and saliva of rheumatoid arthritis patients were compared and was highly significant with a p-value < 0.001. Conclusion: In Group R 86.6% of patients had salivary anti-CCP levels proportionallyincreasing with their serum anti-CCP values with high significance. The given results of this study have shown statistically and clinically significant values and suggest that evaluation of salivary anti-CCP has a promising role in diagnosis of rheumatoid arthritis patients.