Neuromodulation: Letting Sources of Spinal Dopamine Speak for Themselves

نویسندگان

  • Sandeep Kishore
  • David L. McLean
چکیده

A recent study of dopaminergic neurons in the brain of larval zebrafish has important implications for interpreting the natural actions of neuromodulators in the spinal cord.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

(PNS) injection of the adenoviral and adeno-associated viral vectors (rAAV) results in segmental delivery of recombinant genes to spinal cord sensory and motor neurons

a. Specific Aims Advancements in both neuroscience and engineering have provided neurosurgery with new paradigms for the restoration of neural function. In particular, the dual emergence of accurate stereotaxis and deep brain stimulation (DBS) have generated a revolution in the application of targeted neuromodulation. DBS allows for focused reversible inhibition of neural function, while advanc...

متن کامل

Purinergic Signalling in the CNS

Purinergic neurotransmission, involving release of ATP as an efferent neurotransmitter was first proposed in 1972. Later it was recognised as a cotransmitter in peripheral nerves and more recently as a cotransmitter with glutamate, noradrenaline, GABA, acetylcholine and dopamine in the CNS. Both ion channel and G protein-coupled receptors for purines and pyrimidines are widely expressed in the ...

متن کامل

Neuronal Networks of Movement Slc10a4 as a Modulator & Dmrt3 as a Gait-keeper

Larhammar, M. 2014. Neuronal Networks of Movement. Slc10a4 as a Modulator & Dmrt3 as a Gait-keeper. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1026. 58 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9030-0. Nerve cells are organized into complex networks that comprise the building blocks of our nervous system. Neurons communicate by trans...

متن کامل

Is pulsed radiofrequency a neuromodulation technique?

In this issue of Neuromodulation, J. Van Zundert et al. have published an article titled, Percutane-ous pulsed radiofrequency treatment of the cervi-cal dorsal root ganglion in the treatment of chronic cervical pain syndromes: A clinical audit (1). The question that our readers might ask is this: Is pulsed radiofrequency neuromodulation? It is the opinion of these authors that it is. The exact ...

متن کامل

Spinal Cord Stimulation: The Clinical Application of New Technology

The use of neuromodulation for pain relief is among the fastest-growing areas of medicine, involving many diverse specialties and impacting on hundreds of thousands of patients with numerous disorders worldwide. As the evidence of efficacy improves, the interest in spinal cord stimulation (SCS) will increase because it is minimally invasive, safe, and a reversible treatment modality with limite...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Current Biology

دوره 25  شماره 

صفحات  -

تاریخ انتشار 2015