Bioinspired, releasable quorum sensing modulators.

نویسندگان

  • José Gomes
  • Alexander Grunau
  • Adrien K Lawrence
  • Leo Eberl
  • Karl Gademann
چکیده

We demonstrate the synthesis and immobilization of natural product hybrids featuring an acyl-homoserine lactone and a nitrodopamine onto biocompatible TiO(2) surfaces through an operationally simple dip-and-rinse procedure. The resulting immobilized hybrids were shown to be powerful quorum sensing (QS) activators in Pseudomonas strains acting by slow release from the surface.

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عنوان ژورنال:
  • Chemical communications

دوره 49 2  شماره 

صفحات  -

تاریخ انتشار 2013