The aerobic inhibition of glycolysis associated with brain mitochondria.
نویسنده
چکیده
منابع مشابه
The inhibition of oxidative phosphorylation.
Loomis & Lipmann (1948) showed that low concentrations of 2:4-dinitrophenol (DNP) reversibly uncouple the phosphorylation associated with the oxidation of glutamate. This supported the hypothesis that agents such as DNP, which prevent the use of the energy provided by respiration and glycolysis, do so by inhibiting the formation of highenergy phosphate bonds (Lardy & Elvehjem, 1945; McElroy, 19...
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The inhibition of glycolysis by respiration (Pasteur effect) and the inhibition of respiration by glycolysis (Crabtree effect) represent nonhormonal regulatory mechanisms of cellular metabolism. Some of the previous work on these phenomena in intact cells will be reviewed in subsequent papers (1, 2) together with a report on recent experimental work on ascites tumor cells. The difficulty of obt...
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 86 شماره
صفحات -
تاریخ انتشار 1963