Prevention of transition from incipient to overt nephropathy with telmisartan in patients with type 2 diabetes.

نویسندگان

  • Hirofumi Makino
  • Masakazu Haneda
  • Tetsuya Babazono
  • Tatsumi Moriya
  • Sadayoshi Ito
  • Yasuhiko Iwamoto
  • Ryuzo Kawamori
  • Masahiro Takeuchi
  • Shigehiro Katayama
چکیده

1 Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan 2 Division of Metabolism and Biosystemic Science, Asahikawa Medical College, Hokkaido, Japan 3 Division of Nephrology and Hypertension, Diabetes Center, Tokyo Women's Medical University School of Medicine, Tokyo, Japan 4 Department of Endocrinology, Diabetes and Metabolism, Kitasato University School of Medicine, Kanagawa, Japan Division of Nephrology, Tohoku University Graduate Medical School, Miyagi, Japan 6 Department of Medicine, Diabetes Center, Tokyo Women's Medical University School of Medicine, Tokyo, Japan 7 Department of Medicine, Medical School, Juntendo University, Tokyo, Japan 8 Division of Biostatistics, School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan 9 Division of Endocrinology and Diabetes, Department of Medicine, Saitama Medical School, Saitama, Japan

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Relationship between Serum Homocysteine and Other Parameters in Overt Diabetic Nephropathy

OBJECTIVE: Level of serum homocysteine is remarkably common among patients with moderate to sever renal failure. We assessed whether serum homocysteine concentrations were correlated with proteinuria in overt diabetic nephropathy. MATERIALS AND METHODS: A cross-sectional study was carried out on 45 patients (29 males, 16 females) with overt proteinuria. All subjects had type 2 diabetes. Data i...

متن کامل

Telmisartan lowers albuminuria in type 2 diabetic patients treated with angiotensin enzyme inhibitors.

PURPOSE Angiotensin-converting-enzyme inhibitors (ACEIs) provide renal protection in patients with type 2 diabetes and microalbuminuria. MATERIAL AND METHODS In the presented study we followed 34 stable, type 2 diabetic patients with persistent albuminuria treated with maximal doses of ACEIs as a part of their anti-hypertensive treatment. Telmisartan--an angiotensin receptor blocker (ARB)--in...

متن کامل

Effects of Folic Acid Supplementation on Proteinuria in Type 2 Diabetic Patients with Overt Proteinuria

Objective: An association between high homocysteine levels and proteinuria in diabetic nephropathy has been shown. On the other hand, supplementation with folic acid lowers homocysteine concentration. We have studied the effects of folic acid supplementation on proteinuria in type 2 diabetic patients with overt proteinuria. Materials and Methods: Forty five (29 men and 16 women) type 2 diabe...

متن کامل

Prevention and treatment of diabetic nephropathy: the program for irbesartan mortality and morbidity evaluation.

Aggressive treatment of hypertension is effective in reducing both microvascular and macrovascular complications in type 2 diabetes, with target BP < 130/80 mmHg being recommended. Angiotensin-converting enzyme inhibitors were found to be more effective than the other traditional agents in reducing the onset of clinical proteinuria in individuals with both type 1 and type 2 diabetes and incipie...

متن کامل

Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy.

BACKGROUND Renin-angiotensin system blockade reduces proteinuria and prevents nephropathy progression in patients with type 2 diabetes mellitus (T2D). Experimental evidence demonstrates that angiotensin receptor blockers (ARBs) possess anti-inflammatory potential, which might contribute to reducing proteinuria and providing renoprotection. METHODS We conducted a multicentre, double-blind, pro...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Diabetes care

دوره 30 6  شماره 

صفحات  -

تاریخ انتشار 2007