Non-steroidal Antiinflammatory Drugs (nsaids)
نویسنده
چکیده
The non-steroidal antiinflammatory drugs (NSAIDs) are widely used for the treatment of minor pain and for the management of edema and tissue damage resulting from inflammatory joint disease (arthritis). A number of these drugs possess antipyretic activity in addition to having analgesic and antiinflammatory actions, and thus have utility in the treatment of fever. Most of these drugs express their therapeutic actions by inhibition of prostaglandin biosynthesis as described in the sections that follow. Some of the primary indications for NSAID therapy include:
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Diagnosis and Treatment of Ocular Diseases in the Horse
BACTERIAL KERATITIS Simple, uninfected cases of corneal ulceration can be treated with prophylactic antibiotics, mydriatics and systemic antiinflammatory agents. However, aggressive medical therapy is indicated in all cases of confirmed or suspected bacterial keratitis. This includes topical and systemic antimicrobial drugs, mydriatics and antiproteases, and sysemic non-steroidal antiinflammato...
متن کاملNonsteroidal antiinflammatory drugs, acetaminophen, and hypertension.
Selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) as well as acetaminophen belong to the most widely prescribed therapeutic agents worldwide. Their efficacy in pain relief notwithstanding, the use of NSAIDs is associated with an increased cardiovascular risk, which can be partly attributed to their blood pressure raising potential. Adequately powered placebo-controlled ...
متن کاملOverview of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Resource Limited Countries
Non-steroidal anti-inflammatory drugs (NSAIDs) belong to a wide class of therapeutic agents with analgesic and antiinflammatory properties that inhibit the two recognized isoenzymes of prostaglandin G/H synthase (also known as cyclooxygenase (COX)) known as, COX 1 and COX 2 [1,2]. Since the therapeutic action of these drugs is highly mediated by inhibition of COX 2, and their gastrointestinal a...
متن کاملLack of effect of naltrindole on the spinal synergism of morphine and non-steroidal anti-inflammatory drugs (NSAIDS).
To enhance analgesia, combination of analgesics drugs of proven efficacy is a strategy which is accompanied by a reduction of adverse effects. The present study was undertaken to characterize the antinociceptive interaction of morphine with different non-steroidal anti-inflammatory drugs (NSAIDs) using isobolographic analysis and the writhing test of mice. One of the possible mechanisms of acti...
متن کاملInvestigation of Anti-Dermatophytic Effects of Non-Steroidal Anti-Inflammatory Drugs on Trichophyton Mentagrophytes and Epidermophyton Floccosum
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common pharmacological group that has three primary therapeutic effects including anti-inflammatory, anti-pyrexia, and analgesia. In this study, seven of NSAIDs were tested against two species of skin pathogenic fungi (dermatophytes). Percentage inhibition was determined for effective agents. Diclofenac, Aspirin and Naproxen showed muc...
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