Author's response to reviews Title: Testing for Heterogeneity among the Components of a Binary Composite Outcome in a Clinical Trial Authors:

Testing for heterogeneity among the components of a binary composite outcome in a clinical trial

BACKGROUND Investigators designing clinical trials often use composite outcomes to overcome many statistical issues. Trialists want to maximize power to show a statistically significant treatment effect and avoid inflation of Type I error rate due to evaluation of multiple individual clinical outcomes. However, if the treatment effect is not similar among the components of this composite outcom...

Author's response to reviews Title: Usefulness of C-reactive protein testing in acute cough: an open cluster-randomised clinical trial with CRP testing in the intervention group Authors:

Author's response to reviews Title:Sexual behaviour, sexually transmitted infections and attitudes to chlamydia testing among a unique national sample of young Australians: baseline data from a randomised controlled trial Authors:

Author's response to reviews Title: Facilitated patient feedback can improve the quality of nursing care: an exploratory cluster randomised controlled trial Authors:

Author's response to reviews Title: Cancer incidence in registered nurses potentially exposed to antineoplastic drugs and adverse pregnancy outcome incidence in their offspring Authors:

Title: Cancer incidence in registered nurses potentially exposed to antineoplastic drugs and adverse pregnancy outcome incidence in their offspring