Insertional mutagenesis to generate lantibiotic resistance in Lactococcus lactis.

نویسندگان

  • Caitriona M Guinane
  • Paul D Cotter
  • Elaine M Lawton
  • Colin Hill
  • R Paul Ross
چکیده

While the potential emergence of food spoilage and pathogenic bacteria with resistance to lantibiotics is a concern, the creation of derivatives of starter cultures and adjuncts that can grow in the presence of these antimicrobials may have applications in food fermentations. Here a bank of Lactococcus lactis IL1403 mutants was created and screened, and a number of novel genetic loci involved in lantibiotic resistance were identified.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 73 14  شماره 

صفحات  -

تاریخ انتشار 2007