Inducible and Plasmid Mediated AmpC Beta-Lactamase among Klebsiella pneumoniae in a Tertiary Care Teaching Hospital of South India
نویسندگان
چکیده
Amp C beta-lactamases are a type of cephalosporinase enzymes belonging to Class C of Ambler’s structural classification, while assigned to group 3 in the functional classification scheme of Bush (Ambler, 1980; Bush et al., 1995). These enzymes can be either chromosomal or plasmid encoded conferring resistance to both oxyimino (cefotaxime, ceftazidime, ceftriaxone) and 7-α methoxy cephalosporins (cefoxitin or cefotetan) and are not affected by βlactamase inhibitors (clavulanate, sulbactam, tazobactam) (Phillipon et al., 2002). Plasmid mediated Amp C βlactamases are not International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 2 (2017) pp. 1665-1672 Journal homepage: http://www.ijcmas.com
منابع مشابه
Phenotypic Identification and Antibiotic Susceptibility Pattern of AmpC beta-Lactamase Producing Escherichia coli and Klebsiella pneumoniae Isolated from Urinary Tract Infections from a Tertiary Care Hospital of Rawalpindi, Pakistan
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