indolent lymphoma 309 QUALITY OF LIFE MEASURES IN ‘ASYMPTOMATIC’ PATIENTS WITH FOLLICULAR LYMPHOMA (FL) AT PRESENTATION
نویسندگان
چکیده
K. Ardeshna, W. Qian, P. Smith, L. Stevens, C. Pocock, M. Dyer, J. Davies, D. Cunningham, A. Kruger, D. Linch Department of Haematology, University College London Hospital, London, United Kingdom, On Behalf of UK NCRI Lymphoma Clinical Studies Group, MRC, Clinical Trials Unit, Oxford, United Kingdom, CR UK and UCL, Cancer Trials Center, London, United Kingdom, East Kent Hospitals, Canterbury, United Kingdom, East Kent Hospitals, Leicester, United Kingdom, Western General Hospital, Edinburgh, United Kingdom, Royal Marsden Hospital, Sutton, United Kingdom, Royal Cornwall Hospital, Truro, United Kingdom, University College London, London, United Kingdom
منابع مشابه
Primary Follicular Lymphoma of the Conjunctiva in a 12 Year-Old Male
Abstract Background Follicular lymphoma (FL) is the second most common adnexal lymphoma of the eye that almost all of them are reported in elderly patients. Primary FL of the eye has been reported in only two children. Pediatric FL appears to be biologically distinct from typical adult FL. In cases without other organ involvement excision alone with close monitoring is a treatment of choic...
متن کاملChylous pleural effusion: A rare presentation of Non-Hodgkin- Lymphoma
Chylous pleural effusion is characterized by milky-appearing fluid with elevated triglyceride content and presence of chylomicrons in the pleural space. Even though patients with lymphoma sometimes present with malignant pleural effusion, chylous effusion is rarely encountered as a presenting feature in such patients. We present a 47-year-old woman diagnosed as follicular lymphoma who presented...
متن کاملUtility of immunohistochemistry with an antibody against MYC at the initial diagnosis of follicular lymphoma, grade 3A, for predicting a more aggressive clinical course: a case report and review of the literature.
Follicular lymphoma (FL) is the most common indolent lymphoma, and associated with the chromosomal translocation t(14;18)(q32;q21). While, FL harboring both BCL2 and MYC translocation at diagnosis is very rare. The evaluation of MYC expression in typical FL at presentation using southern blot, G-banded karyotyping or fluorescence in situ hybridization (FISH) analyses has been described so far. ...
متن کاملA Rare Presentation of In Situ Mantle Cell Lymphoma and Follicular Lymphoma: A Case Report and Review of the Literature
A 65-year-old gentleman presented with left groin swelling over the course of two months. Physical exam revealed nontender left inguinal adenopathy, and computed tomography scans detected multiple lymph nodes in the mesenteric, aortocaval, and right common iliac regions. An excisional lymph node biopsy was performed. Pathologic evaluation demonstrated follicular center site which stained positi...
متن کاملTransformation of follicular lymphoma to plasmablastic lymphoma with c-myc gene rearrangement.
Follicular lymphoma (FL) is an indolent lymphoma that transforms to high-grade lymphoma, mostly diffuse large B-cell lymphoma, in about a third of patients. We present the first report of a case of FL that transformed to plasmablastic lymphoma (PBL). Clonal transformation of the FL to PBL was evidenced by identical IGH/BCL2 gene rearrangements and VDJ gene usage in rearranged IGH genes. IGH/ BC...
متن کامل