Statins in Critical Care
نویسندگان
چکیده
The role of statin drugs in the reduction of serum lipids has been well documented. More recently we have evidences which suggest that statins may positively impact many organ systems and disease states independent of lipid reduction. These have added a wide scope of potential targets for statin therapy ranging from plaque stabilization in acute coronary syndrome (ACS) to decreasing loss of renal function; lowering mortality in patients with diastolic heart failure; to prevention and treatment of stroke. This review summarizes the evidence in favor of role of statins in intensive care unit and briefly discuss the role of statins in prevention and treatment of sepsis as a potential future application of statins in critical care (see Table 1).
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