Quantifying Nanoparticle-Cell Interactions
نویسندگان
چکیده
Nanoparticles are finding increasing applications in the field of medicine [1], with extensive research being conducted on the design of nanoparticles to enhance targeted uptake and action [2]. Preliminary investigations of nanoparticles with potential applications in medicine involve in vitro testing to explore cellular uptake (particle dose) and action. Analytical transmission electron microscopy (TEM) is a valuable tool for the intracellular localization of nanoparticles and for the development of mechanistic modes of action. TEM studies can be conducted on the nanoparticles prior to in vitro delivery and subsequent to it on ultrathin sections of cells.
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