Red cell storage: does duration matter?
نویسنده
چکیده
The report by Solomon et al in this issue of Blood is a welcome addition to understanding the clinical impact of prolonged red cell storage.
منابع مشابه
Extending Storage Duration of Mother Scales for Enlarging Scale Bulblets and Soluble Carbohydrates Content in Lily “Arabian Red”
Oriental hybrid lily “Arabian Red” mother scales were stored in moist cocopeat and perlite (1:1) for 3 or 5 months at 25 ̊C. The numbers of scale bulblets per mother scale were nearly identical in two durations. Increasing storage duration promoted the growth of roots (number and length) and No. scales per scale bulblets. And, diameters of scale bulblets were more in longer storage duration (5 m...
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BACKGROUND Prolonged storage of packed red blood cells (PRBCs) may increase morbidity and mortality, and patients having massive transfusion might be especially susceptible. We therefore tested the hypothesis that prolonged storage increases mortality in patients receiving massive transfusion after trauma or nontrauma surgery. Secondarily, we considered the extent to which storage effects diffe...
متن کاملAge of red blood cells and transfusion in critically ill patients
Red blood cells (RBC) storage facilitates the supply of RBC to meet the clinical demand for transfusion and to avoid wastage. However, RBC storage is associated with adverse changes in erythrocytes and their preservation medium. These changes are responsible for functional alterations and for the accumulation of potentially injurious bioreactive substances. They also may have clinically harmful...
متن کاملEffect of Duration of Packed Red Blood Cell Storage on Morbidity and Mortality in Dogs After Transfusion: 3,095 cases (2001–2010)
BACKGROUND Accumulating evidence suggests that transfusion of packed red blood cells (PRBCs) stored for >14 days is associated with increased rates of sepsis, multiple organ dysfunction, and mortality in human patients. OBJECTIVE To determine if duration of PRBC storage has an effect on morbidity and mortality in dogs after transfusion. ANIMALS Dogs admitted to the Matthew J Ryan Veterinary...
متن کاملBlood transfusion in the critically ill: does storage age matter?
Morphologic and biochemical changes occur during red cell storage prior to product expiry, and these changes may hinder erythrocyte viability and function following transfusion. Despite a relatively large body of literature detailing the metabolic and structural deterioration that occurs during red cell storage, evidence for a significant detrimental clinical effect related to the transfusion o...
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ورودعنوان ژورنال:
- Blood
دوره 121 9 شماره
صفحات -
تاریخ انتشار 2013