Eudesman-12,8/%olides and Other Terpenes from Artemisia Species

The aerial parts of Artemisia iwayomogi afforded, in addition to already known terpenes, eleven new eudesmanolides whereas four new guaianolides were found in A. gmelinii. No sesquiterpene lactones were detected in the aerial parts of A. santolinifolia which afforded two new nerolidol derivatives besides several other already known compounds. From A. caerulescens var. cretacea six eudesmanolides were isolated, one of which has not been reported previously. The structures were elucidated by high field ‘H NMR spectroscopy and chemical transformations. The chemotaxonomic significance of sesquiterpene lactones within the section Abrotanum and the subgenus Seriphidium is briefly discussed.