Cellular Requirements for the Primary in Vitro Antibody Response to Dnp-ficoll

نویسندگان

  • D. E. Mosier
  • B. M. Johnson
  • W. E. Paul
  • P. R. B. McMaster
چکیده

The cellular requirements for the primary in vitro IgM and IgG response to dinitrophenyl-substituted Ficoll were examined. Neither thymus-derived lymphocytes nor macrophage-rich splenic adherent cells were required for anti-DNP antibody synthesis. DNP-Ficoll is therefore tentatively classified as a "thymic-independent" antigen.

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عنوان ژورنال:
  • The Journal of Experimental Medicine

دوره 139  شماره 

صفحات  -

تاریخ انتشار 1974