Thermal adaptation of the crucian carp ( Carassius carassius ) cardiac delayed
نویسندگان
چکیده
6 7 8 Minna Hassinen, Salla Laulaja, Vesa Paajanen, Jaakko Haverinen and Matti Vornanen 9 University of Eastern Finland, Department of Biology, P.O. Box 111, 80101 Joensuu, Finland 10 11 12 13 Short title: Thermal adaptation of cardiac potassium current in crucian carp 14 15 16 17 Address for correspondence: 18 Matti Vornanen 19 University of Eastern Finland 20 Department of Biology, P.O. box 111 21 80101 Joensuu, Finland 22 Email: [email protected] 23 Phone: +358 132513383 24 25 26 Articles in PresS. Am J Physiol Regul Integr Comp Physiol (April 20, 2011). doi:10.1152/ajpregu.00067.2011
منابع مشابه
Thermal adaptation of the crucian carp (Carassius carassius) cardiac delayed rectifier current, IKs, by homomeric assembly of Kv7.1 subunits without MinK.
Ectothermic vertebrates experience acute and chronic temperature changes which affect cardiac excitability and may threaten electrical stability of the heart. Nevertheless, ectothermic hearts function over wide range of temperatures without cardiac arrhythmias, probably due to special molecular adaptations. We examine function and molecular basis of the slow delayed rectifier K(+) current (I(Ks...
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The crucian carp (Carassius carassius) seems unique among vertebrates in its ability to maintain cardiac performance during prolonged anoxia. We investigated whether this phenomenon arises in part from a myocardium tolerant to severe acidosis or because the anoxic crucian carp heart may not experience a severe extracellular acidosis due to the fish's ability to convert lactate to ethanol. Spont...
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Like most vertebrates, humans die within minutes when deprived of molecular oxygen (anoxia), in part because of cardiac failure. In contrast, some freshwater turtles can survive anoxia for months at low temperatures, but to do so, they drastically suppress cardiac activity and autonomic cardiovascular control. Although Carassius carassius, the crucian carp, shares this anoxia tolerance, we show...
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A patch-clamp analysis of L-type Ca2+ current in ventricular myocytes of cold- and warm-acclimated rainbow trout (Oncorhynchus mykiss) and crucian carp (Carassius carassius) hearts was performed. Trout were acclimated at 4 and 17 degrees C and carp at 4 and 24 degrees C for a minimum of 4 weeks. Ventricular myocytes were isolated by enzymatic dissociation using collagenase and trypsin. Marked s...
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The crucian carp (Carassius carassius L.) exhibits the unique ability among vertebrates to maintain cardiac performance at normoxic levels during prolonged anoxia exposure. This thesis investigates the hypothesis that this phenomenon is possible because the heart likely never experiences an extracellular pH below 7.4 due to the fish’s exclusive trait of converting lactate and H ions to ethanol....
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