Electrophoresis of colloidal biological particles.

Biological rarticles in liquid suspension exhibit varied electrophoretie mobili:y dependent upon the electric charge behavior of their surface constituents. The surface composition of a population of the same kind of biological particles is uniform in a constant environment. The microscope electrophoresis techniques for mobility and isoelectric point determinations of microscopic particles (bacteria, suspended maminalian tissue cells, aluminum oxide particles, and polystyrene latex particles) and submicroscopic pa•ticles (proteins and gelatin) are described. The information that can be obtained and the additives for modification of electrophoretic mobility determined by the analytical method are applied to the preparative, laminar-flow, continuous particle electrophoresis system. Separation of bacteria and bacteriophage from suspensions by continuous particle electrophoresis is described.