Complement Fixation Tests in Chronic Infective Deforming Arthritis and Arthritis Deformans
نویسنده
چکیده
1. From a comparison of the results with arthritis deformans recorded in tables III, IV, and VI, and with the control cases recorded in table VII, one is justified in concluding that Streptococcus viridans is an infectious agent and excites the production of a complement-fixing substance (fixateur) in the organism in cases of arthritis deformans, and, therefore, Streptococcus viridans is the probable causative agent of the disease in many cases of arthritis deformans. Probably 40 per cent. and more of cases of arthritis deformans should be considered as chronic infective deforming arthritis. 2. Rarely the clinical manifestations of arthritis deformans may be due to gonococcus infection. 3. The serum from one case may react positively to two different organisms, most frequently to Streptococcus viridans and to gonococcus, when the reaction to the former should be considered the indicator of the causative agent, since with the latter infection is often latent in the genito-urinary tract. Incidence of gonococcus infection is high and the clinical manifestations of arthritis deformans are rarely produced by gonococcus infection.
منابع مشابه
همراهی بین آرتریت پسوریاتیک با شدت درگیری ناخن در بیماران مبتلا به پسوریازیس مراجعهکننده به درمانگاه پوست بیمارستان رازی در سالهای 1386 و 1387
Background and Aim: Psoriasis is a chronic skin disorder involving many parts of the body including skin, nails and joints with severe negative effects on patient's quality of life. Nail involvement is one of the most difficult involvements of this disease to treat. Psoriatic arthritis categorized in sero-negative spondilo-arthropaties with some deforming characteristics. The aim of the present...
متن کاملA Flowcytometry Study of CD55 and CD59 Expression on Erythrocytes in Rheumatoid Arthritis Patients
Background: Inappropriate activation or blockage of the inhibition of complement system could cause tissue damages in autoimmune diseases particularly rheumatoid arthritis (RA). Defect in complement component regulation may cause damages to tissues, on the other hand, or the damaged tissue might affect the unnecessary activation of complement components. Objective: To investigate the expressi...
متن کاملStatus of self- care ability of patients with Rheumatoid Arthritis
Abstract Introduction: Today medical world is facing the increase of chronic diseases. Rheumatoid Arthritis as a chronic disease causes pain, fatigue, limited mobility and daily activity, physical function disorder and disability. An important part of controlling chronic illnesses such as rheumatoid arthritis is enabling patients to conduct self-care and adjusting to condition of chronic d...
متن کاملHistopathological changes of the antigen-induced chronic arthritis in the knee joint of the rabbit
Background and Objectives: The cause and pathophysiology of rheumatoid arthritis has not been fully understood and an experimental model of this disease is essential for research on the problem. In this research study, establishment and histopathological changes of chronic arthritis due to intra-articula...
متن کاملImmune complexes and rheumatoid factors in canine arthritides.
Thirty two domestic dogs with naturally occurring polyarthritis were investigated to determine the contribution of autoimmunity in the pathological mechanisms. Comparisons were made with canine infective arthritis (12 dogs), osteoarthritis (32), and osteoarthritis secondary to rupture of the cranial cruciate ligament (19). Rheumatoid factors, immune complexes, and complement fixation (C1q bindi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 20 شماره
صفحات -
تاریخ انتشار 2003