Genomics of in-stent restenosis: early insights into a complex disease.
نویسندگان
چکیده
Inflammation is a key component of atherosclerosis. Abundant preclinical data support the hypothesis that atherosclerosis is a chronic inflammatory disorder.1,2 Indeed, clinical trial data now provide evidence that inflammation, as reflected in serum markers such as C-reactive protein and interleukin-6, is a strong risk factor for the development and progression of atherosclerosis.3,4 The role of genetic factors in determining a predisposition or susceptibility to inflammation that exacerbates atherosclerosis is not fully known.
منابع مشابه
Overview of Intracoronary Brachytherapy for in-Stent Restenosis of a Drug-Eluting Stent
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OBJECTIVE To assess the effectiveness of routine sirolimus eluting stent (SES) implantation for unselected patients with in-stent restenosis and to provide preliminary information about the angiographic outcome for lesion subgroups and for different in-stent restenosis patterns. DESIGN Prospective, single centre registry. SETTING Tertiary referral centre. PATIENTS 44 consecutive patients ...
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ورودعنوان ژورنال:
- Circulation
دوره 112 16 شماره
صفحات -
تاریخ انتشار 2005