Labelling of sucralfate using technetium labelled bovine serum albumin--an alternate to Tc99m-HSA.
نویسندگان
چکیده
Technetium labelled Sucralphate has been used as an ulcer scanning agent in the gastrointestinal tract. The labelling described in the literature involves incubation of Tc99m-HSA (Human serum albumin) with Sucralphate. Due to difficulty in obtaining HSA we used bovine serum albumin (BSA) to tag radioactivity with Sucralphate. The radioactive yields (Tagged Sucraiphate and Tc99m-BSA) obtained after purification were more than 99% pure and stable for several hours. Animal and human trials showed good localisation of the agent in ulcer bed (JPMA 38: 241, 1988).
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ورودعنوان ژورنال:
- JPMA. The Journal of the Pakistan Medical Association
دوره 38 9 شماره
صفحات -
تاریخ انتشار 1988