[Controversial issues in congenital nevi].

نویسندگان

  • S Paradela
  • R Fernández-Torres
  • E Fonseca
چکیده

Congenital melanocytic nevi are very common lesions that nevertheless pose many controversial questions. A systematic review of the literature suggests that the risk of developing melanoma on giant congenital melanocytic nevi (GCMN) is lower than previously thought given that, in the most recent series of GCMN, only 2 % of patients developed melanoma and most did so before the age of 5 years. Therefore,prophylactic surgery should be considered on an individual basis according to the degree of clinical suspicion of melanoma and the esthetic and functional consequences.In extensive reviews of series of biopsies of melanoma, small congenital melanocytic nevi have been associated with 7 % to 8 % of cases. Many authors believe that these might represent a significant risk of malignant conversion from 10 years onwards and so recommend regular control visits during infancy and prophylactic exeresis in puberty.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Skin-Fat Composite Grafts after Excisions of Medium Sized Congenital Melanocytic Nevi in Children

Congenital melanocytic nevi (CMN) are defined as melanocytic nevi that present at birth or within the first few months of life. Small or medium-sized nevi occur in approximately 1% to 6% of all newborns, whereas giant nevi occur in approximately 1 in 20,000 [1-3]. There are two main considerations in the treatment of CMN. The first is predicting the risk of its transformation to melanoma, and t...

متن کامل

Speckled lentiginous nevus: within the spectrum of congenital melanocytic nevi.

BACKGROUND Currently, there is disagreement as to whether speckled lentiginous nevi (nevi spili) are congenital or acquired pigmented lesions. Part of this controversy is related to the natural history of these lesions that often present at birth as hyperpigmented patches and then take several years to reach their more readily recognized spotted form. Arguments in favor of speckled lentiginous ...

متن کامل

High frequency of BRAFV600E mutation in acquired nevi and small congenital nevi, but low frequency of mutation in medium-sized congenital nevi.

To investigate whether the frequency of the BRAF(V600E) (V-raf murine sarcoma virus oncogene homolog B1) mutation in melanocytic nevi is associated with sun exposure patterns, we examined 120 acquired melanocytic nevi excised from various anatomic sites, including glabrous skin, as well as 62 congenital nevi. We used a new mutation detection system based on the shifted termination assay, called...

متن کامل

Pigmented Skin Lesions in Children (Melanocytic Nevus, Clonal Nevus and Halo Nevus) — Symptoms and Treatment

Benign pigmented skin lesions are very common in children and can be generally classified into congenital or acquired nevi. Congenital nevi can be small, medium or large. Large nevi are usually associated with a higher risk of malignant transformation into melanoma. Acquired melanocytic nevi can be classified into typical melanocytic nevi, clonal nevi, or halo nevi. Cytological atypia can be ob...

متن کامل

Pilomatrixoma Arising Juxtaposed to Congenital Melanocytic Nevi: Concern for Malignant Degeneration? A Previously Unreported Association

Figure 1. Preoperative photograph showing the overlying melanocytic nevi. DESCRIPTION We present a 13-year-old male patient with congenital melanocytic nevi and a yearlong history of enlarging right preauricular mass. Examination revealed 2 congenital melanocytic nevi overlying a large, firm, mobile 2.7 × 2.5-cm subcutaneous mass with irregular borders. Pathology confirmed intradermal melanocyt...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Actas dermo-sifiliograficas

دوره 100 7  شماره 

صفحات  -

تاریخ انتشار 2009