A highly enantioselective intramolecular Heck reaction with a monodentate ligand.
نویسندگان
چکیده
An efficient enantioselective intramolecular Heck reaction of cyclohexadienones, using readily available and modular TADDOL-based mono- and bidentate phosphoramidites as chiral ligands and not requiring any additives, has been developed. Excellent enantioselectivities up to 96% ee are reached for the first time in a Heck reaction with monodentate ligands.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 124 2 شماره
صفحات -
تاریخ انتشار 2002