Magnification chromoendoscopy in comparison to standard chromoendoscopy for detection of intestinal metaplasia in renal transplant recipients.

The importance of magnification chromoendoscopy with methylene blue in detecting specialized intestinal metaplasia in short segment Barrett’s esophagus

Background Barrett esophagus is an acquired, premalignant condition caused by chronic gastroesophageal refllux, in which the normal squamous epithelium in the distal esophagus is replaced by columnar epithelium. Barrett’s esophagus is considered to follow a multistep process progression from intestinal metaplasia to low-grade dysplasia (LGD) to high-grade dysplasia (HGD) and finally to esophage...

Diagnostic yield of methylene blue chromoendoscopy for detecting specialized intestinal metaplasia and dysplasia in Barrett's esophagus: a meta-analysis.

BACKGROUND The reported yield of methylene-blue (MB) chromoendoscopy targeted biopsy in detecting specialized intestinal metaplasia (SIM) and, more importantly, dysplasia in patients with Barrett's esophagus (BE) has shown variable results. OBJECTIVE To perform a meta-analysis of published studies for assessment of the diagnostic yield of techniques of chromoendoscopy compared with convention...

A prospective comparative study of narrow-band imaging, chromoendoscopy, and conventional colonoscopy in the diagnosis of colorectal neoplasia.

BACKGROUND Discrimination between neoplastic and non-neoplastic lesions is crucial in colorectal cancer screening. Application of narrow-band imaging (NBI) in colonoscopy visualises mucosal vascular networks in neoplastic lesions and may improve diagnostic accuracy. AIM To compare the diagnostic efficacy of NBI in differentiating neoplastic from non-neoplastic colorectal lesions with diagnost...

Magnifying Endoscopy and Chromoendoscopy in Atrophic Gastritis, Intestinal Metaplasia and Gastric Dysplasia

External validation of a classification for methylene blue magnification chromoendoscopy in premalignant gastric lesions.

BACKGROUND Conventional endoscopy has low sensitivity, specificity, and interobserver agreement for the diagnosis of gastric atrophy, intestinal metaplasia, and dysplasia. Magnification chromoendoscopy (ME) may optimize the evaluation of premalignant gastric lesions. OBJECTIVE AND DESIGN As part of a multicenter trial, we aimed at validating a previously proposed classification for gastric me...