Oncostatin M Modulation of Lipid Storage
نویسندگان
چکیده
Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological functions of insulin-sensitive tissues. In this review, the actions of OSM in adipose tissue and liver are discussed, with an emphasis on lipid metabolism.
منابع مشابه
اثر 6 هفته تمرین هوازی بر حجم تومور و سطح سرمی انکوستاتین-ام در موشهای مبتلا به سرطان پستان
Background and Objectives: Breast cancer is a major health concern in women, but it seems that exercise plays an important role in controlling it. Therefore, the aim of the present study was to examine the effects of six weeks of aerobic training on the tumor volume and oncostatin-M serum level in mice with breast cancer. Materials and Methods: This research was an experimental...
متن کاملLipid Oxidation in M. longissimus dorsi and M. semimembranosus in Lambs Reared Indoors and on Pasture
Lipid oxidation was studied in M. longissimusdorsiand M. semimembranosusin male lambs of Northeastern Bulgarian Fine Wool Breed and cross of this breed with Ile de France, reared indoors and on pasture. The oxidation of the lipids was determined by quantification of thiobarbituric acid reactive substances (TBARS), formed during the storage of the muscles at 4 ˚С until 6th dayand -20 ˚С until 90...
متن کاملAntioxidant properties of sodium acetate, sodium citrate and sodium lactate on lipid oxidation in rainbow trout (Onchorhynchus mykiss) sticks during refrigerated storage (4˚C)
This study was carried out to investigate the rate of lipid oxidation in fresh rainbow trout (Onchorhynchus mykiss) and in the sticks treated by (2.5% w/v) sodium acetate (NaA), sodium citrate (NaC) and sodium lactate (NaL). The pH value, free fatty acid (FFA), thiobarbituric acid (TBA) and sensory evaluation (odor, flavor and color) were determined on 0, 3, 6, 9 and 12 days of storage. The r...
متن کاملInduction of "antigen silencing" in melanomas by oncostatin M: down-modulation of melanocyte antigen expression.
We previously reported that antigen expression in melanoma cell lines is down-regulated by proteins secreted by antigen-negative melanoma cells. Here we report the purification and characterization of one of these down-regulatory factors, the cytokine, oncostatin M (OSM), which transmits its signal via the gp130 cell surface receptor, resulting in the selective down-modulation of the melanocyte...
متن کاملAntioxidant properties of sodium acetate, sodium citrate and sodium lactate on lipid oxidation in rainbow trout (Onchorhynchus mykiss) sticks during refrigerated storage (4˚C)
This study was carried out to investigate the rate of lipid oxidation in fresh rainbow trout (Onchorhynchus mykiss) and in the sticks treated by (2.5% w/v) sodium acetate (NaA), sodium citrate (NaC) and sodium lactate (NaL). The pH value, free fatty acid (FFA), thiobarbituric acid (TBA) and sensory evaluation (odor, flavor and color) were determined on 0, 3, 6, 9 and 12 days of storage. The r...
متن کامل