Characterization of peripheral osmoreceptors
نویسندگان
چکیده
منابع مشابه
The Molecular and Cellular Identity of Peripheral Osmoreceptors
In mammals, the osmolality of the extracellular fluid (ECF) is highly stable despite radical changes in salt/water intake and excretion. Afferent systems are required to detect hypo- or hyperosmotic shifts in the ECF to trigger homeostatic control of osmolality. In humans, a pressor reflex is triggered by simply drinking water which may be mediated by peripheral osmoreceptors. Here, we identifi...
متن کاملAENDO July 40/1
Carlson, Scott H., and J. Michael Wyss. Hepatic denervation does not affect plasma vasopressin response to intragastric hypertonic saline in conscious rats. Am. J. Physiol. 277 (Endocrinol. Metab. 40): E161–E167, 1999.—Peripheral osmoreceptors monitor dietary NaCl and modify central nervous system and renal sympathetic nervous system activity accordingly. Experimental evidence suggests that the...
متن کاملHepatic denervation does not affect plasma vasopressin response to intragastric hypertonic saline in conscious rats.
Peripheral osmoreceptors monitor dietary NaCl and modify central nervous system and renal sympathetic nervous system activity accordingly. Experimental evidence suggests that these responses are dependent on the hepatic nerves. Peripheral osmoreceptors also modify arginine vasopressin (AVP) secretion. However, although hepatic denervation reportedly blunts activation of both supraoptic and para...
متن کاملHepatic denervation chronically elevates arterial pressure in Wistar-Kyoto rats.
Several lines of evidence suggest that peripheral osmoreceptors respond to alterations in dietary NaCl by adjusting renal sympathetic nerve activity, but the impact of this reflex on the long-term regulation of mean arterial pressure (MAP) remains unclear. The present study tested the hypothesis that denervation of peripheral osmoreceptors elevates arterial pressure and induces NaCl-sensitive h...
متن کاملThe area postrema modulates hypothalamic Fos responses to intragastric hypertonic saline in conscious rats.
We have recently reported that an acute intragastric hypertonic saline load increases Fos immunoreactivity in several central nuclei, including the supraoptic nucleus (SON), paraventricular nucleus (PVN), nucleus of the solitary tract (NTS), area postrema (AP), and lateral parabrachial nucleus (LPBN). We have also shown that these responses are mediated by stimulation of peripheral osmoreceptor...
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