Enhancing 2-iodoxybenzoic acid reactivity by exploiting a hypervalent twist.
نویسندگان
چکیده
A rearrangement of hypervalent bonds, or twisting, proves to be the rate-determining step in the 2-iodoxybenzoic acid (IBX) oxidation of alcohols. From this insight, derived from density functional theory calculations, we explain why IBX oxidizes large alcohols faster than small ones and propose a modification to the reagent predicted to make it more active.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 127 41 شماره
صفحات -
تاریخ انتشار 2005