Correct estimation of parameters for ultrasound nuchal translucency screening.

نویسندگان

  • K H Nicolaides
  • R J Snijders
  • H S Cuckle
چکیده

Johnson, S. (1996). Down’s syndrome screening in the UK, Lancet, 347, 906–907. Pandya, P.P., Snijders, R.J.M., Johnson, S.P., de Loudes Brizot, M., Nicolaides, K.H. (1995). Screening for fetal trisomies by maternal age and fetal nuchal translucency thickness at 10 to 14 weeks of gestation, Br. J. Obstet. Gynaecol., 102, 957–962. Schuchter, K., Wald, N.J., Hackshaw, A.K., Hafner, E., Liebhardt, E. (1998). The distribution of nuchal translucency at 10–13 weeks of pregnancy, Prenat. Diagn., 18, 281–286. Wald, N.J., George, L., Smith, D., Densem, J.W., Petterson, K. (1996). On behalf of the International Prenatal Screening Research Group. Serum screening for Down’s syndrome between 8 and 14 weeks of pregnancy, Br. J. Obstet. Gynaecol., 103, 407– 412. Wald, N.J., Hackshaw, A.K. (1997). Combining ultrasound and biochemistry in first-trimester screening for Down’s syndrome, Prenat. Diagn., 17, 821–829. Wald, N.J., Kennard, A., Hackshaw, A., McGuire, A. (1997). Antenatal screening for Down’s syndrome, J. Med. Screren, 4, 181–246. Wald, N.J., Stone, R., Cuckle, H.S., Grudzinskas, J.G., Barkai, G., Brambati, B., Teisner, B., Fuhrmann, W. (1992). First trimester concentrations of PAPP-A and placental protein 14 in Down’s syndrome, BMJ, 305, 28.

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Nuchal translucency: an ultrasound marker for fetal chromosomal abnormalities.

CONTEXT The literature shows an association between several ultrasound markers and chromosome abnormality. Among these, measurement of nuchal translucency has been indicated as a screening method for aneuploidy. The trisomy of chromosome 21 has been most evaluated. OBJECTIVE To define the best fixed cutoff point for nuchal translucency, with the assistance of the ROC curve, and its accuracy i...

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Background: Prenatal diagnosis for Fetal Chromosomal anomalies currently relies on assessment of risk followed by a combination of biochemical and nuchal translucency. Trisomy 21 is the most common trisomy that is associated with intellectual disability. Pregnant women who receive a prenatal diagnosis of trisomy 21 currently have the option of continuing or terminating their pregnancy, but no f...

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عنوان ژورنال:
  • Prenatal diagnosis

دوره 18 5  شماره 

صفحات  -

تاریخ انتشار 1998