1,1,1-Trichloro-2,2-bis(4-ethoxyphenyl)ethane
نویسنده
چکیده
In the title compound, C(18)H(19)Cl(3)O(2), which is the 4-eth-oxy-phenyl analogue of the insecticidally active 4-meth-oxy-phenyl compound meth-oxy-chlor, the dihedral angle between the two benzene rings is 60.38 (13)°. An intra-molecular aromatic C-H⋯Cl inter-action is present.
منابع مشابه
1,1,1-Trichloro-2,2-bis(4-iodophenyl)ethane
In the structure of the title compound, C(14)H(9)Cl(3)I(2), which is the 4-iodo-phenyl analogue of the insecticide DDT [1,1,1-tri-chloro-2,2-bis-(4-chloro-phen-yl)ethane], isomorphism between the two compounds has been confirmed. In the mol-ecule, the dihedral angle between the planes of the two benzene rings is 65.8 (4)° which compares with 64.7 (7)° in DDT.
متن کاملMetabolism of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane, and 1-chloro-2,2-bis(p-chlorophenyl)ethene in the hamster.
The urinary metabolites of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD), and 1-chloro-2,2-bis(p-chlorophenyl)ethene in female hamsters are reported. The principal metabolite of both DDT and DDD is 2,2-bis(p-chlorophenyl) acetic acid. DDT- and DDD-treated animals also excreted small amounts of DDD, 1-chloro-2,2-bis(p-chlorophenyl)ethene, 1...
متن کاملProducts Formed from Analogues of 1,1,1-Trichloro-2,2-Bis(p-Chlorophenyl) Ethane (DDT) Metabolites by Pseudomonas putida.
Cultures of Pseudomonas putida growing in solutions with diphenylmethane as sole carbon source formed 1,1,1',1'-tetraphenyldimethyl ether. The product was identified by gas chromatography, mass spectrometry, and infrared and nuclear magnetic resonance spectrometry. The formation of benzophenone, benzhydrol, and phenylglycolic acid was established by gas chromatography and mass spectrometry. Sim...
متن کاملShort Communication Mechanism of Induction of Cytochrome P450 Enzymes by the Proestrogenic Endocrine Disruptor Pesticide-Methoxychlor: Interactions of Methoxychlor Metabolites with the Constitutive Androstane Receptor System
Methoxychlor, a structural analog of the DDT pesticide, was previously shown to induce rat hepatic CYP2B and -3A mRNAs and the corresponding proteins [J Biochem Mol Toxicol 1998;12:315– 323], Additionally, methoxychlor was found to activate the constitutive androstane receptor (CAR) system and induce CYP2B6 (J Biol Chem 1999;274:6043–6046), suggesting a mechanism for methoxychlor-mediated cytoc...
متن کاملMechanism of induction of cytochrome p450 enzymes by the proestrogenic endocrine disruptor pesticide-methoxychlor: interactions of methoxychlor metabolites with the constitutive androstane receptor system.
Methoxychlor, a structural analog of the DDT pesticide, was previously shown to induce rat hepatic CYP2B and -3A mRNAs and the corresponding proteins [J Biochem Mol Toxicol 1998;12:315-323], Additionally, methoxychlor was found to activate the constitutive androstane receptor (CAR) system and induce CYP2B6 (J Biol Chem 1999;274:6043-6046), suggesting a mechanism for methoxychlor-mediated cytoch...
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