Long-lived fluorescence of homopolymeric guanine-cytosine DNA duplexes.

نویسندگان

  • Ignacio Vayá
  • Pascale Changenet-Barret
  • Thomas Gustavsson
  • Dragoslav Zikich
  • Alexander B Kotlyar
  • Dimitra Markovitsi
چکیده

The fluorescence spectrum of the homopolymeric double helix poly(dG) x poly(dC) is dominated by emission decaying on the nanosecond time-scale, as previously reported for the alternating homologue poly(dGdC) x poly(dGdC). Thus, energy trapping over long periods of time is a common feature of GC duplexes which contrast with AT duplexes. The impact of such behaviour on DNA photodamage needs to be evaluated.

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عنوان ژورنال:
  • Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

دوره 9 9  شماره 

صفحات  -

تاریخ انتشار 2010