Chemical rescue of protein tyrosine phosphatase activity.
نویسندگان
چکیده
We report that the activity of a rationally engineered protein tyrosine phosphatase (PTP) mutant can be fully rescued by the addition of the biarsenical fluorescein derivative FlAsH, a compound that does not affect the activity of wild-type PTPs.
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ورودعنوان ژورنال:
- Chemical communications
دوره 46 4 شماره
صفحات -
تاریخ انتشار 2010