Perspective study on pamidronate in stage I multiple myeloma.
نویسندگان
چکیده
منابع مشابه
Economic evaluation of zoledronic acid versus pamidronate for the prevention of skeletal-related events in metastatic breast cancer and multiple myeloma.
Skeletal complications of cancer decrease health-related quality of life. Bisphosphonates can prevent skeletal-related events. We collected resource use data prospectively for 930 patients alongside a multinational trial of zoledronic acid versus pamidronate for patients with metastatic multiple myeloma or breast cancer and > or =1 bone lesion. Country-specific unit costs were assigned to count...
متن کاملبررسی سطح سرمی پروتئین آلفا-1-آنتی تریپسین با روش زون کاپیلاری الکتروفورز در بیماران مبتلا به سرطان مولتیپل میلوما در مرحله‌‌ی یک بیماری
Background & Aims: Acute phase proteins are synthesized mainly by the liver and macrophages in an inflammatory conditions as a result of some trauma and malignancies. Increased levels of these proteins have been reported in many cancer tumors and multiple myeloma as an important indicator of prognosis of malignancies. Because of importance of this issue, we investigate the serum level ...
متن کامل[Effect of pamidronate infusion time on renal function in patients with multiple myeloma].
INTRODUCTION Administration of biphosphonates in patients with renal failure requires a dosage adjustment. OBJECTIVES Analyse renal function evolution in multiple myeloma patients after reducing infusion time for 90 mg pamidronate by 2 h. METHODS In 2007, a retrospective study was carried out on all patients who presented multiple myeloma and bone metastasis treated with pamidronate adminis...
متن کاملIn Silico Investigations of the Anti-Catabolic Effects of Pamidronate and Denosumab on Multiple Myeloma-Induced Bone Disease
It is unclear whether the new anti-catabolic agent denosumab represents a viable alternative to the widely used anti-catabolic agent pamidronate in the treatment of Multiple Myeloma (MM)-induced bone disease. This lack of clarity primarily stems from the lack of sufficient clinical investigations, which are costly and time consuming. However, in silico investigations require less time and expen...
متن کاملReversibility of pamidronate-associated glomerulosclerosis.
Bisphosphonates such as pamidronate are widely used in the treatment of patients with lytic bony lesions secondary to breast cancer or multiple myeloma, yet they have been associated with deterioration of renal function and histopathological changes in the kidney. There have been recent reports associating the use of pamidronate with the development of the collapsing variant of focal segmental ...
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ورودعنوان ژورنال:
- The hematology journal : the official journal of the European Haematology Association
دوره 4 6 شماره
صفحات -
تاریخ انتشار 2003