Current Concepts in Pontine Myelinolysis: Review of Literature
نویسندگان
چکیده
Pontine myelinolysis (PM) was first described in 1959 by Adams et al. in alcoholic patients [1]. Also known as osmotic demyelination syndrome (ODS), PM is subdivided into central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) [2]. Each is identified at the level of demyelination either centered within the pons [1] or outside the pons [3], respectively. While the etiology of ODS is poorly understood, it is believed that rapid correction of sodium in chronic hyponatremia is implicated as primary factor [1].
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